Chronic myeloid leukaemia following repeated exposure to chest radiography and computed tomography in a patient with pneumothorax: A case report and literature review
نویسندگان
چکیده
It is well known that radioactive rays may cause damage to the human body. Progress in modern medicine has led to an increased risk of therapeutic and diagnostic radiation exposure of patients. Although clear evidence of a radiation dose-dependent risk of chronic myeloid leukaemia, particularly for patients exposed to radiation at a young age, has been established, it is not known whether radiation exposure during diagnostic imaging also increases the risk of cancer. The present study reports the case of a patient who underwent several diagnostic imaging tests (including repeated chest radiography and computed tomography) for recurrent pneumothorax. At around one year subsequent to these tests, the patient was diagnosed with chronic myeloid leukaemia. The patient exhibited an increase in white blood cell count over time, and a bone marrow smear test showed a myeloid/erythroid ratio of 13.9:1. In addition, the qualitative breakpoint cluster region (BCR)/Abelson (ABL) gene test revealed positive results for BCR/ABL fusion (p210). Based on the data reported in the current case, research aimed at elucidating the potential risks associated with diagnostic radiation is urgently required. It is crucial that medical professionals consider the potential harmful side effects of diagnostic radiation when ordering radiation-based diagnostic imaging examinations.
منابع مشابه
Chronic myeloid leukemia following colon cancer treatment: A case report and literature review
Background: Solid tumors may occur in 3% of the patients with chronic myeloid leukemia (CML). In this paper, we presented a case of CML following treatment of colon cancer. Case Presentation: A 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. Following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...
متن کاملA Rare Preterm Newborn Case of Rib Osteomyelitis with Intrathoracic Involvement
Background: Rib osteomyelitis is a very rare form of pediatric osteomyelitis. Case report: Herein, we reported a very rare case of chest wall abscess with rib osteomyelitis and rib destruction due to Staphylococcus aureus infection in a 14-day-old preterm male neonate. The diagnosis of this uncommon disease requires a high index of suspicion due to its rarity and non-specific clinical presenta...
متن کاملDose Reduction Methods in Chest Computed Tomography
Introduction: Computed tomography is one of the most powerful tools for investigating thorax disease, because it shows progression of lung disease much clearer than chest radiography. Technical advances in CT scanners have led to some abilities for CT scanners such as coverage of larger volume, lower noise and ability for acquiring image in one respiratory phase. However, this will be accompani...
متن کاملA Huge Lymphangioma Mimicking Pleural Effusion with Extension to Both Chest Cavities: A Case Report and Review of Literature
Mediastinal lymphangioma is primarily a benign lesion and the majority of the cases are found incidentally. These lesions account for approximately 1% of all mediastinal tumors. Here we present a giant mediastinal cystic mass in a 35-year-old female who was presented with severe respiratory distress. On the plain chest radiography and CT scan, a massive left pleural effusion with large paraster...
متن کاملMassive Emphysema and Pneumothorax Following Shoulder Arthroscopy under General Anaesthesia: A Case Report
The patient was a 61-year-old female with massive rotator cuff tear who had no history of smoking, COPD, asthma, or other pulmonary diseases. Four hours following shoulder arthroscopy, the patient developed progressive dyspnea, which was diagnosed as pneumothorax with subcutaneous emphysema extending to the neck and face. Chest tube was inserted promptly. The patient was discharged with a good ...
متن کامل